W2R (p.Trp2Arg) variant of LAG3 (P18627)
W2R (p.Trp2Arg) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
W2R (p.Trp2Arg) variant details
- p.Trp2Arg
- gnomAD 12-6772856-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0687
- REVEL 0.03
- CADD 8.93
- PolyPhen-2 0.00
- SIFT 0.27
- Population evidence available
- Structural context available
- Literature evidence available