W2C (p.Trp2Cys) variant of LAG3 (P18627)
W2C (p.Trp2Cys) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
W2C (p.Trp2Cys) variant details
- p.Trp2Cys
- gnomAD 12-6772858-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.205
- REVEL 0.06
- CADD 24.70
- PolyPhen-2 0.43
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available