W16L (p.Trp16Leu) variant of LAG3 (P18627)
W16L (p.Trp16Leu) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
W16L (p.Trp16Leu) variant details
- p.Trp16Leu
- cosmic curated COSV99179
- Ensembl rs976491768
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.11
- CADD 23.50
- PolyPhen-2 0.29
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available