V61A (p.Val61Ala) variant of LAG3 (P18627)
V61A (p.Val61Ala) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
V61A (p.Val61Ala) variant details
- p.Val61Ala
- gnomAD 12-6773315-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.07
- CADD 23.90
- PolyPhen-2 0.28
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available