V17M (p.Val17Met) variant of LAG3 (P18627)
V17M (p.Val17Met) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
V17M (p.Val17Met) variant details
- p.Val17Met
- gnomAD 12-6772901-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.231
- REVEL 0.06
- CADD 20.50
- PolyPhen-2 0.43
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available