V17A (p.Val17Ala) variant of LAG3 (P18627)
V17A (p.Val17Ala) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
V17A (p.Val17Ala) variant details
- p.Val17Ala
- gnomAD rs1941859729
- Missense
- Variant Prioritization Score for Impact Estimate 0.0581
- REVEL 0.03
- CADD 4.94
- PolyPhen-2 0.00
- SIFT 0.29
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available