T47I (p.Thr47Ile) variant of LAG3 (P18627)
T47I (p.Thr47Ile) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
T47I (p.Thr47Ile) variant details
- p.Thr47Ile
- gnomAD 12-6773273-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.04
- CADD 18.60
- PolyPhen-2 0.22
- SIFT 0.02
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available