S45N (p.Ser45Asn) variant of LAG3 (P18627)
S45N (p.Ser45Asn) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
S45N (p.Ser45Asn) variant details
- p.Ser45Asn
- gnomAD 12-6773267-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.03
- CADD 18.10
- PolyPhen-2 0.23
- SIFT 0.06
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available