S45I (p.Ser45Ile) variant of LAG3 (P18627)
S45I (p.Ser45Ile) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
S45I (p.Ser45Ile) variant details
- p.Ser45Ile
- gnomAD 12-6773267-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.03
- CADD 18.80
- PolyPhen-2 0.02
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available