P72T (p.Pro72Thr) variant of LAG3 (P18627)
P72T (p.Pro72Thr) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
P72T (p.Pro72Thr) variant details
- p.Pro72Thr
- ExAC rs771448332
- TOPMed rs771448332
- gnomAD rs771448332
- Missense
- Variant Prioritization Score for Impact Estimate 0.106
- REVEL 0.02
- CADD 9.76
- PolyPhen-2 0.06
- SIFT 0.07
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available