P72H (p.Pro72His) variant of LAG3 (P18627)
P72H (p.Pro72His) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
P72H (p.Pro72His) variant details
- p.Pro72His
- gnomAD 12-6773705-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.152
- REVEL 0.09
- CADD 21.90
- PolyPhen-2 0.54
- SIFT 0.02
- Most common in the East Asian population (allele frequency 6.9e-05)
- Structural context available
- Literature evidence available