P71L (p.Pro71Leu) variant of LAG3 (P18627)
P71L (p.Pro71Leu) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
P71L (p.Pro71Leu) variant details
- p.Pro71Leu
- ExAC rs749595028
- gnomAD rs749595028
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.03
- CADD 16.80
- PolyPhen-2 0.12
- SIFT 0.01
- Most common in the East Asian population (allele frequency 3.4e-05)
- Structural context available