P67S (p.Pro67Ser) variant of LAG3 (P18627)
P67S (p.Pro67Ser) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
P67S (p.Pro67Ser) variant details
- p.Pro67Ser
- ESP rs149722682
- ExAC rs149722682
- TOPMed rs149722682
- gnomAD rs149722682
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.06
- CADD 23.80
- PolyPhen-2 0.42
- SIFT 0.01
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available