P49T (p.Pro49Thr) variant of LAG3 (P18627)
P49T (p.Pro49Thr) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
P49T (p.Pro49Thr) variant details
- p.Pro49Thr
- TOPMed rs953432394
- gnomAD rs953432394
- Missense
- Variant Prioritization Score for Impact Estimate 0.323
- REVEL 0.03
- CADD 16.60
- PolyPhen-2 0.02
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available