P43S (p.Pro43Ser) variant of LAG3 (P18627)
P43S (p.Pro43Ser) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
P43S (p.Pro43Ser) variant details
- p.Pro43Ser
- 1000Genomes rs781221749
- ExAC rs781221749
- gnomAD rs781221749
- Missense
- Variant Prioritization Score for Impact Estimate 0.375
- REVEL 0.15
- CADD 25.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available