P43L (p.Pro43Leu) variant of LAG3 (P18627)
P43L (p.Pro43Leu) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
P43L (p.Pro43Leu) variant details
- p.Pro43Leu
- gnomAD 12-6773261-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.479
- REVEL 0.25
- CADD 26.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available