P43A (p.Pro43Ala) variant of LAG3 (P18627)
P43A (p.Pro43Ala) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
P43A (p.Pro43Ala) variant details
- p.Pro43Ala
- cosmic curated COSV52568
- 1000Genomes rs781221749
- ExAC rs781221749
- gnomAD rs781221749
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.18
- CADD 25.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00038)
- Structural context available