P25S (p.Pro25Ser) variant of LAG3 (P18627)
P25S (p.Pro25Ser) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
P25S (p.Pro25Ser) variant details
- p.Pro25Ser
- cosmic curated COSV52568
- 1000Genomes rs146038483
- ESP rs146038483
- ExAC rs146038483
- Missense
- Variant Prioritization Score for Impact Estimate 0.154
- REVEL 0.05
- CADD 11.10
- PolyPhen-2 0.04
- SIFT 0.18
- Most common in the HGDP:BASQUE population (allele frequency 0.091)
- Structural context available