P22R (p.Pro22Arg) variant of LAG3 (P18627)
P22R (p.Pro22Arg) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
P22R (p.Pro22Arg) variant details
- p.Pro22Arg
- TOPMed rs1941862507
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- REVEL 0.04
- CADD 17.60
- PolyPhen-2 0.02
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available