P22L (p.Pro22Leu) variant of LAG3 (P18627)
P22L (p.Pro22Leu) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
P22L (p.Pro22Leu) variant details
- p.Pro22Leu
- gnomAD 12-6773198-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.247
- REVEL 0.05
- CADD 18.50
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available