P19S (p.Pro19Ser) variant of LAG3 (P18627)
P19S (p.Pro19Ser) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
P19S (p.Pro19Ser) variant details
- p.Pro19Ser
- ExAC rs768527438
- gnomAD rs768527438
- Missense
- Variant Prioritization Score for Impact Estimate 0.233
- REVEL 0.07
- CADD 20.50
- PolyPhen-2 0.01
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available