P14L (p.Pro14Leu) variant of LAG3 (P18627)
P14L (p.Pro14Leu) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
P14L (p.Pro14Leu) variant details
- p.Pro14Leu
- TOPMed rs1014999225
- gnomAD rs1014999225
- Missense
- Variant Prioritization Score for Impact Estimate 0.176
- REVEL 0.03
- CADD 3.96
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 7e-05)
- Structural context available