P14A (p.Pro14Ala) variant of LAG3 (P18627)
P14A (p.Pro14Ala) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
P14A (p.Pro14Ala) variant details
- p.Pro14Ala
- gnomAD 12-6772892-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.03
- CADD 11.30
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available