L23F (p.Leu23Phe) variant of LAG3 (P18627)
L23F (p.Leu23Phe) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
L23F (p.Leu23Phe) variant details
- p.Leu23Phe
- TOPMed rs1393242900
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.02
- CADD 13.70
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available