L15R (p.Leu15Arg) variant of LAG3 (P18627)
L15R (p.Leu15Arg) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
L15R (p.Leu15Arg) variant details
- p.Leu15Arg
- gnomAD 12-6772896-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- REVEL 0.24
- CADD 21.20
- PolyPhen-2 0.69
- SIFT 0.15
- Population evidence available
- Structural context available
- Literature evidence available