L15F (p.Leu15Phe) variant of LAG3 (P18627)
L15F (p.Leu15Phe) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
L15F (p.Leu15Phe) variant details
- p.Leu15Phe
- gnomAD 12-6772895-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.08
- CADD 23.50
- PolyPhen-2 0.90
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available