I48V (p.Ile48Val) variant of LAG3 (P18627)
I48V (p.Ile48Val) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
I48V (p.Ile48Val) variant details
- p.Ile48Val
- gnomAD 12-6773275-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0688
- REVEL 0.02
- CADD 11.00
- PolyPhen-2 0.00
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available
- Literature evidence available