I48T (p.Ile48Thr) variant of LAG3 (P18627)
I48T (p.Ile48Thr) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
I48T (p.Ile48Thr) variant details
- p.Ile48Thr
- ExAC rs770557883
- gnomAD rs770557883
- Missense
- Variant Prioritization Score for Impact Estimate 0.0487
- REVEL 0.01
- CADD 6.26
- PolyPhen-2 0.00
- SIFT 0.21
- Most common in the South Asian population (allele frequency 4.6e-05)
- Structural context available