I48M (p.Ile48Met) variant of LAG3 (P18627)
I48M (p.Ile48Met) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
I48M (p.Ile48Met) variant details
- p.Ile48Met
- gnomAD 12-6773277-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.125
- REVEL 0.04
- CADD 15.80
- PolyPhen-2 0.05
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available