G8S (p.Gly8Ser) variant of LAG3 (P18627)
G8S (p.Gly8Ser) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
G8S (p.Gly8Ser) variant details
- p.Gly8Ser
- TOPMed rs1941859458
- gnomAD rs1941859458
- Missense
- Variant Prioritization Score for Impact Estimate 0.178
- REVEL 0.08
- CADD 21.70
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available