G8D (p.Gly8Asp) variant of LAG3 (P18627)
G8D (p.Gly8Asp) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
G8D (p.Gly8Asp) variant details
- p.Gly8Asp
- gnomAD 12-6772875-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.121
- REVEL 0.01
- CADD 17.90
- PolyPhen-2 0.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available