G70S (p.Gly70Ser) variant of LAG3 (P18627)
G70S (p.Gly70Ser) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
G70S (p.Gly70Ser) variant details
- p.Gly70Ser
- gnomAD rs1158947650
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- REVEL 0.03
- CADD 16.30
- PolyPhen-2 0.01
- SIFT 0.36
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available