G70D (p.Gly70Asp) variant of LAG3 (P18627)
G70D (p.Gly70Asp) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data, published literature, and structural context.
G70D (p.Gly70Asp) variant details
- p.Gly70Asp
- gnomAD 12-6773699-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0397
- REVEL 0.01
- CADD 3.43
- PolyPhen-2 0.00
- SIFT 0.36
- Most common in the Latino/Admixed American population (allele frequency 6.8e-05)
- Structural context available
- Literature evidence available