G70C (p.Gly70Cys) variant of LAG3 (P18627)
G70C (p.Gly70Cys) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
G70C (p.Gly70Cys) variant details
- p.Gly70Cys
- gnomAD 12-6773698-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.06
- CADD 18.60
- PolyPhen-2 0.61
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available