E36D (p.Glu36Asp) variant of LAG3 (P18627)
E36D (p.Glu36Asp) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
E36D (p.Glu36Asp) variant details
- p.Glu36Asp
- gnomAD 12-6773241-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.08
- CADD 23.30
- PolyPhen-2 0.88
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available