D68G (p.Asp68Gly) variant of LAG3 (P18627)
D68G (p.Asp68Gly) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
D68G (p.Asp68Gly) variant details
- p.Asp68Gly
- gnomAD 12-6773336-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.06
- CADD 23.80
- PolyPhen-2 0.30
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available