D68E (p.Asp68Glu) variant of LAG3 (P18627)
D68E (p.Asp68Glu) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
D68E (p.Asp68Glu) variant details
- p.Asp68Glu
- TOPMed rs1941864502
- gnomAD rs1941864502
- Missense
- Variant Prioritization Score for Impact Estimate 0.148
- REVEL 0.02
- CADD 20.70
- PolyPhen-2 0.01
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available