C44Y (p.Cys44Tyr) variant of LAG3 (P18627)
C44Y (p.Cys44Tyr) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
C44Y (p.Cys44Tyr) variant details
- p.Cys44Tyr
- ExAC rs752704799
- gnomAD rs752704799
- Missense
- Variant Prioritization Score for Impact Estimate 0.61
- REVEL 0.47
- CADD 28.20
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available