A75T (p.Ala75Thr) variant of LAG3 (P18627)
A75T (p.Ala75Thr) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
A75T (p.Ala75Thr) variant details
- p.Ala75Thr
- TOPMed rs1419243888
- Missense
- Variant Prioritization Score for Impact Estimate 0.06
- REVEL 0.01
- CADD 8.41
- PolyPhen-2 0.00
- SIFT 0.39
- Most common in the Non-Finnish European population (allele frequency 2e-06)
- Structural context available