A75S (p.Ala75Ser) variant of LAG3 (P18627)
A75S (p.Ala75Ser) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data, published literature, and structural context.
A75S (p.Ala75Ser) variant details
- p.Ala75Ser
- gnomAD 12-6773713-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0514
- REVEL 0.01
- CADD 6.25
- PolyPhen-2 0.00
- SIFT 0.50
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available
- Literature evidence available