A74V (p.Ala74Val) variant of LAG3 (P18627)
A74V (p.Ala74Val) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
A74V (p.Ala74Val) variant details
- p.Ala74Val
- gnomAD rs1941869321
- Missense
- Variant Prioritization Score for Impact Estimate 0.122
- REVEL 0.03
- CADD 11.90
- PolyPhen-2 0.01
- SIFT 0.08
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available