A74T (p.Ala74Thr) variant of LAG3 (P18627)
A74T (p.Ala74Thr) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
A74T (p.Ala74Thr) variant details
- p.Ala74Thr
- gnomAD 12-6773710-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0777
- REVEL 0.01
- CADD 6.96
- PolyPhen-2 0.00
- SIFT 0.35
- Population evidence available
- Structural context available
- Literature evidence available