A74S (p.Ala74Ser) variant of LAG3 (P18627)
A74S (p.Ala74Ser) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
A74S (p.Ala74Ser) variant details
- p.Ala74Ser
- gnomAD 12-6773710-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0708
- REVEL 0.01
- CADD 4.37
- PolyPhen-2 0.00
- SIFT 0.48
- Population evidence available
- Structural context available
- Literature evidence available