A74R (p.Ala74Arg) variant of LAG3 (P18627)
A74R (p.Ala74Arg) in LAG3 (P18627) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
A74R (p.Ala74Arg) variant details
- p.Ala74Arg
- rs1941869032
- gnomAD 12-6773698-G-GGCC
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.345
- CADD 20.90
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available
- Literature evidence available