A74D (p.Ala74Asp) variant of LAG3 (P18627)
A74D (p.Ala74Asp) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
A74D (p.Ala74Asp) variant details
- p.Ala74Asp
- gnomAD 12-6773711-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.126
- REVEL 0.04
- CADD 11.30
- PolyPhen-2 0.01
- SIFT 0.14
- Population evidence available
- Structural context available
- Literature evidence available