A59V (p.Ala59Val) variant of LAG3 (P18627)
A59V (p.Ala59Val) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
A59V (p.Ala59Val) variant details
- p.Ala59Val
- gnomAD 12-6773309-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.01
- CADD 13.50
- PolyPhen-2 0.00
- SIFT 0.40
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available