A59T (p.Ala59Thr) variant of LAG3 (P18627)
A59T (p.Ala59Thr) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
A59T (p.Ala59Thr) variant details
- p.Ala59Thr
- gnomAD 12-6773308-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.146
- REVEL 0.03
- CADD 14.40
- PolyPhen-2 0.01
- SIFT 0.53
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available