A38P (p.Ala38Pro) variant of LAG3 (P18627)
A38P (p.Ala38Pro) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
A38P (p.Ala38Pro) variant details
- p.Ala38Pro
- gnomAD 12-6773245-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.199
- REVEL 0.09
- CADD 24.40
- PolyPhen-2 0.88
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available