A34V (p.Ala34Val) variant of LAG3 (P18627)
A34V (p.Ala34Val) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
A34V (p.Ala34Val) variant details
- p.Ala34Val
- gnomAD 12-6773234-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.05
- CADD 22.90
- PolyPhen-2 0.16
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available
- Literature evidence available