A34S (p.Ala34Ser) variant of LAG3 (P18627)
A34S (p.Ala34Ser) in LAG3 (P18627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
A34S (p.Ala34Ser) variant details
- p.Ala34Ser
- ExAC rs766752202
- TOPMed rs766752202
- gnomAD rs766752202
- Missense
- Variant Prioritization Score for Impact Estimate 0.401
- REVEL 0.12
- CADD 26.30
- PolyPhen-2 0.85
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available